IMSEAM

Equipment

The equipment if the Biomechanics Core Facility is separated in 2 groups. The first one to measure the properties of the materials, such as elastic properties, viscoelastic properties and hardness. The second group of devices includes sample preparation methods using cryo-technics.

 

In order to standardize reproducible mechanical characterizations of soft (bio)materials, tissues and cells, the Biomechanics Core Facility is working as a team with the users and with good communication to share the knowledges and know-how. It is important to mention and discuss the parameters of the experiment in scientific publications to guarantee reproducibility and comparability.

 

The Biomechanics Core Facility is taking care of the calibration and other maintenances.If you have any question about the device or its accessories, do not hesitate to contact us!

CONTACT

Biomechanics Core Facility

IMSEAM - University Heidelberg

INF 225, D-69120 Heidelberg

Lab: 99.361 + 02.362

 

Coordinator Florine Sessler, M.Sc.

+49 6221 54 15718

Office: 02.361

 

   

BIOMECHANICS EQUIPMENT

RHEOMETER - DISCOVERY HYBRID 20 - TA INSTRUMENTS

 

 

For characterizing bulk viscoelastic properties, e.g. of hydrogels and tissues

Equipped with UV unit for photoswitching of samples

Interfacial Rheology: Double Wall Ring

TENSILE TEST DEVICE - 2.5kN ZWICKI – ZWICK&ROELL

Tensile testing of materials

Special setup for compression test

Equipped with 3 load cells for soft materials (5N, 100N, 500N)

NANOINDENTER - PAVONE - OPTICS11LIFE

 

 

 

 

 

 

 

Spatially and mechanically highly precise indentor system based on precalibrated cantilevers: cell stiffness, viscoelasticity, adhesion, contraction, mechanosensing in near-physiological conditions

Equipped with a fluorescence imaging module to improve usage of the system with biological systems

To come: environmental module

FURTHER INSTRUMENTS

Bareiss DigiTest II

Hardness tester for soft tissue and polymers according to shore, IRHD and VLRH. Used for characterizing connective tissue, such as cartilage, soft, and synthetic materials. The setup includes a test stand, a receiving arm with the measuring device for forces up to 20 N, and the electronic measurement and recording unit. The samples are placed on a metal sample holder with a milled edge.

 

Home-built Indentation System

Calibrated indentation system with a mm-sized indenter sphere, suitable for the mechanical characterization of bulk materials.

SPECIMEN PREPARATION EQUIPMENT

CRYO-BALL MILL - RETSCH

 

 

 

The ball mill will be applied for preparation of soft, hard and cryogenic samples for chemical extraction, radical measurement or electron microscopy. The milling cups of metal, ceramic or agate can be used for instance for breaking down hard tissue or polymer samples, and further milling to powder in micrometer size.

CRYOTOME - CRYOSTAR NX50

 

 

For cutting specimens (0.5 μm-500 μm) (such as tissue, organoids or hydrogels) prior to histological and optical characterization.

CAD MODELLING - INVENTOR - AUTODESK

Learn to design of part for 3D printing and more!

Results: files (part, assembly or drawing) as ipt, step, iges, stl and pdf

Possibility to work on Solidworks

FURTHER INSTRUMENTS

Tissue slicer

For cutting alive tissue and hydrogel samples (150 μm) prior to mechanical and optical characterization.